Porgaviximab

A4DAB211 | Phase-II
Zaire Ebolavirus Glycoprotein
G1 / None
Mapp Biopharmaceutical Public Health Agency of Canada National Institute of Allergy and Infectious Diseases
Phase-II
Whole mAb
c2G4-N Zmapp
—
IMGT PubChem (374364165) PubChem (381127997) PubChem (472408628) PubChem (476262940) PubChem (476269579) PubChem (513907280) Thera-SAbDab YAbS
Avg A4D Score
-0.6714
Score Range
-0.67 to -0.67
Structures
3
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB211_5kel_Q_U 5kel 100% -0.6718 6.5 9.0 -0.4363 -0.735
A4DAB211_5kel_P_T 5kel 100% -0.6709 6.5 9.0 -0.4363 -0.7339
A4DAB211_5kel_H_L 5kel 100% -0.6716 6.5 9.0 -0.4416 -0.7333