Masavibart

A4DAB166 | Approved
SARS-CoV-2 Spike RBD
G1 / None
Regeneron Pharmaceuticals
Approved
Whole mAb
ZRC-3308A7 ZRC3308A7 ZRC 3308A7 ZRC-3308 ZRC3308 ZRC 3308
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IMGT PubChem (461453571) PubChem (472424444) PubChem (476262114) PubChem (476269250) PubChem (479821113) PubChem (513907218) Thera-SAbDab YAbS
Avg A4D Score
-0.6336
Score Range
-0.67 to -0.59
Structures
5
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB166_7zjl_l_k 7zjl 100% -0.6699 6.5 4.0 -0.4644 -0.6968
A4DAB166_8j26_B_A 8j26 100% -0.6425 6.5 4.0 -0.4192 -0.7058
A4DAB166_7zjl_j_i 7zjl 100% -0.6528 6.5 9.0 -0.3615 -0.6909
A4DAB166_6xdg_C_A 6xdg 100% -0.6143 6.0 9.0 -0.3863 -0.6456
A4DAB166_8j1q_B_A 8j1q 100% -0.5885 6.5 4.0 -0.4033 -0.641