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A4DAB241 | Infectious diseases | Preregistration
SARS-CoV-2 Spike RBD
G1 / IgG1
AstraZeneca RQ Bio
Preregistration
Whole mAb
AZD3152 AZD-3152
—
Avg A4D Score
-0.6561
Score Range
-0.7 to -0.62
Structures
6
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB241_7zr7_D_E 7zr7 98% -0.6185 7.0 4.0 -0.508 -0.6533
A4DAB241_8suo_H_L 8suo 100% -0.6979 6.5 4.0 -0.4232 -0.7375
A4DAB241_8cbf_H_L 8cbf 98% -0.6634 6.5 4.0 -0.4583 -0.6934
A4DAB241_7zff_H_L 7zff 98% -0.6968 6.5 4.0 -0.4343 -0.7349
A4DAB241_7zr7_H_L 7zr7 98% -0.6187 7.0 4.0 -0.435 -0.6754
A4DAB241_7zr7_F_G 7zr7 98% -0.6413 7.0 4.0 -0.4627 -0.6965