Sebastian Kmiecik photo

Sebastian Kmiecik

Head of the Laboratory

Professor at University of Warsaw and head of Laboratory of Computational Biology at Biological and Chemical Research Centre, University of Warsaw. Member of Laboratory of Theory of Biopolymers at Faculty of Chemistry, University of Warsaw. Former employee and partner of Selvita biotechnology company.

Google Scholar citations, ORCID


Contact

Emailsekmi@chem.uw.edu.pl
Phone(+48) 22 55 26 364Dial the number
AddressRoom 3.132
Biological and Chemical Research Centre
University of Warsaw
Zwirki i Wigury 101
02-089 Warsaw, Poland
rooms 3.132, 3.133

Publications

  1. MAPIYA contact map server for identification and visualization of molecular interactions in proteins and biological complexesNucleic Acids Research: gkac307, 2022Aleksandra E Badaczewska-Dawid, Chandran Nithin, Wróblewski Karol, Kurciński Mateusz, Kmiecik Sebastian
  2. Molecular Dynamics Scoring of Protein–Peptide Models Derived from Coarse-Grained DockingMolecules, 26(11): 3293, 2021Zalewski Mateusz, Kmiecik Sebastian, Koliński Michał
  3. Phosphorylation of the conserved C-terminal domain of ribosomal P-proteins impairs the mode of interaction with plant toxinsFebs Letters, 2021Horbowicz-Drożdżal Patrycja, Kamel Karol, Kmiecik Sebastian, Borkiewicz Lidia, Tumer Nilgun E., Shaw Pang-Chui, Tchórzewski Marek, Grela Przemysław
  4. Protein-protein docking with large-scale backbone flexibility using coarse-grained Monte-Carlo simulationsInternational Journal of Molecular Sciences, 22(14): 7341, 2021Kurciński Mateusz, Kmiecik Sebastian, Zalewski Mateusz, Kolinski Andrzej
  5. Protocols for rational design of protein solubility and aggregation properties using Aggrescan3D standaloneBiorxiv, doi: 10.1101/2020.09.09.276915, 2021Kuriata Aleksander, Badaczewska-Dawid Aleksandra E., Pujols Jordi, Ventura Salvador, Kmiecik Sebastian
  6. Synthetic Transition from Thiourea-Based Compounds to Tetrazole Derivatives: Structure and Biological Evaluation of Synthesized New N-(Furan-2-ylmethyl)-1H-tetrazol-5-amine DerivativesMolecules, 26: 323, 2021Daniel Szulczyk, Anna Bielenica, Piotr Roszkowski, Michał A. Dobrowolski, Wioletta Olejarz, Kmiecik Sebastian, Małgorzata Podsiad, Marta Struga
  7. Computational reconstruction of atomistic protein structures from coarse-grained modelsComputational and Structural Biotechnology Journal, 18: 162-176, 2020Badaczewska-Dawid Aleksandra, Kolinski Andrzej, Kmiecik Sebastian
  8. Docking interactions determine early cleavage events in insulin proteolysis by pepsin: experiment and simulationInternational Journal of Biological Macromolecules, 2020Kolinski Michal, Kmiecik Sebastian, Dec Robert, Piejko Marcin, Mak Pawel, Dzwolak Wojciech
  9. Docking of peptides to GPCRs using a combination of CABS-dock with FlexPepDock refinementBriefings In Bioinformatics, bbaa109, 2020Badaczewska-Dawid Aleksandra E, Kmiecik Sebastian, Koliński Michał
  10. Flexible docking of peptides to proteins using CABS-dockProtein Science, 29: 211–222, 2020Kurciński Mateusz, Badaczewska-Dawid Aleksandra, Kolinski Michal, Kolinski Andrzej, Kmiecik Sebastian
  11. Isoxazole-containing 5′ mRNA cap analogues as inhibitors of the translation initiation processBioorganic Chemistry, 96: 103583, 2020Piecyk Karolina, Lukaszewicz Maciej, Kamel Karol, Janowska Maria, Pietrow Paulina, Kmiecik Sebastian, Jankowska-Anyszka Marzena
  12. Phosphorylation of the N-terminal domain of ribosomal P-stalk protein uL10 governs its association with the ribosomeFebs Letters, 594: 3002-3019, 2020Filipek Kamil, Michalec-Wawiórka Barbara, Boguszewska Aleksandra, Kmiecik Sebastian, Tchórzewski Marek
  13. Protocols for all-atom reconstruction and high-resolution refinement of protein-peptide complex structuresMethods in Molecular Biology, 2165: 273-287, 2020Badaczewska-Dawid Aleksandra, Khramushin Alisa, Kolinski Andrzej, Schueler-Furman Ora, Kmiecik Sebastian
  14. Protocols for fast simulations of protein structure flexibility using CABS-flex and SURPASSMethods in Molecular Biology, 2165: 337-353, 2020Badaczewska-Dawid Aleksandra, Kolinski Andrzej, Kmiecik Sebastian
  15. Aggrescan3D (A3D) 2.0: prediction and engineering of protein solubilityNucleic Acids Research, 47: W300-W307, 2019Kuriata Aleksander, Iglesias Valentin, Pujols Jordi, Kurciński Mateusz, Kmiecik Sebastian, Ventura Salvador

    16. ...And 55 more - see all publications of this author

 

Who we are?

We are group of life science researchers with different backgrounds: chemistry, bioinformatics, physics and medical sciences. We mainly work on development and applications of molecular modeling tools in biology and medicine. Our interests embrace broad aspects of computational biology, from molecular simulations to data analysis.

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